Send to

Choose Destination
Zhongguo Yi Miao He Mian Yi. 2009 Dec;15(6):501-6.

[Meta-analysis on serological effect of the primary vaccination for Japanese encephalitis of the literatures].

[Article in Chinese]

Author information

Department of National Immunization Programme, Chinese Center for Disease Control and Prevention, Beijing 100050, China.



To summary and compare the different seroconversion rates after the primary vaccination for the Japanese encephalitis (JE), and to evaluate the serological effect of 3 kinds of JE vaccines.


Searching "CHKD", "Wanfang" database and "EMCC" databases, the studies of the immunogenicity after the primary JEV vaccination, all randomized controlled trials or non-randomized controlled trials were included, and statistical analysis were made by RevMan 4.2.10 software.


A total of 12 literatures were included, 7 studies had control groups. The seroconversion rates after the primary vaccination, JEV-L, JEV-I (Vero) and JEV-I (PHK), were 86% (95% CI: 80%-91%), 83% (95% CI: 72% -94%) and 64% (95% CI: 58%-69%) respectively. Comparing the seroconversion rates of the 3 kinds of vaccines after primary immunization, the rate of JEV-I (Vero) was significantly higher than the rate of JEV-I (PHK), other comparisons were no significant difference.


The serological effects of JEV-L and JEV-I (Vero) after the primary vaccination were higher than that of JEV-I (PHK).

[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center