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J Acquir Immune Defic Syndr. 2010 Aug;54(4):340-2. doi: 10.1097/QAI.0b013e3181e3dbf6.

Potent in vitro inactivation of both free and cell-associated CCR5- and CXCR4-tropic HIV-1 by common commercial soap bars from South Africa.

Author information

1
Université Paris Descartes (Paris V), and Laboratoire de Virologie, Hôpital Européen Georges Pompidou, Paris, France.

Abstract

We showed herein the potent virucidal effect of soap and water solutions against both CCR5-tropic and CXCR4-tropic cell-free HIV-1 strains, and cytotoxicity for HIV-1-infected lymphocytes during short incubation durations, ranging from 30 seconds to 2 minutes. These observations indicate a rapid inhibitory effect of soap and water on viral infectivity.

PMID:
20517160
DOI:
10.1097/QAI.0b013e3181e3dbf6
[Indexed for MEDLINE]
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