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Caries Res. 2010;44(3):272-6. doi: 10.1159/000314675. Epub 2010 May 27.

Association of oral candidal carriage with dental caries in children.

Author information

1
University of Health Sciences, Lahore, Pakistan. drmahwishraja@hotmail.com

Abstract

INTRODUCTION:

Oral candidiasis is one of the most common opportunistic oral fungal infections. Oral candidal carriage in schoolchildren is a subject of increasing interest worldwide and has recently been associated with increased caries incidence in children.

AIMS:

This study was carried out to identify association between oral candidal carriage in children and dental caries.

SUBJECTS AND METHODS:

One hundred subjects with an age range between 6 and 12 years were included in this study. The subjects were distributed equally into two groups, i.e., study (caries-positive) and control (caries-free) groups. Oral hygiene index and DMFT/dmft scores were recorded for each subject. Sampling for Candida was carried out using intraoral swabs and concentrated oral rinse. Sabouraud dextrose agar containing 0.1 mg/ml of chloramphenicol was used as the primary culture medium. Candida was identified by employing API-20C AUX and germ tube formation tests.

RESULTS:

The subjects in the caries-positive group showed a high frequency of oral candidal carriage compared to the caries-free subjects and the results were statistically very significant (p < 0.01). The odds ratio was 67.37, implying a high caries risk with positive oral candidal carriage (95% CI 14-323).

DISCUSSION:

The findings of this study underscore the possible association of Candida with dental caries.

CONCLUSIONS:

The occurrence of dental caries in children with mixed dentition is positively correlated with the frequency of oral candidal carriage.

PMID:
20516688
DOI:
10.1159/000314675
[Indexed for MEDLINE]

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