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Eur Respir J. 2010 Jun;35(6):1396-406. doi: 10.1183/09031936.00175909.

Pulmonary hypertension in patients with chronic myeloproliferative disorders.

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1
Pulmonary Divison, Carmel Medical Center, Faculty of Medicine, Technion, Institute of Technology, 7 Michal St., Haifa, Israel. adir-sh@zahav.net.il

Abstract

Pulmonary hypertension (PH) is a severe haemodynamic disorder in which the pulmonary artery pressure is persistently elevated, leading to right-sided heart failure and death. Recently, chronic myeloproliferative diseases associated with pulmonary hypertension were included in the group 5 category, corresponding to PH for which the aetiology is unclear and/or multifactorial. In this review we will describe the distinct forms of PH in the context of the myeloproliferative diseases chronic thromboembolic pulmonary hypertension and pre-capillary PH mimicking pulmonary arterial hypertension. The epidemiology, mechanisms and treatment approaches will be discussed.

PMID:
20513911
DOI:
10.1183/09031936.00175909
[Indexed for MEDLINE]
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