Format

Send to

Choose Destination
Bioinformatics. 2010 Jul 15;26(14):1794-6. doi: 10.1093/bioinformatics/btq276. Epub 2010 May 26.

DA 1.0: parameter estimation of biological pathways using data assimilation approach.

Author information

1
NUS Graduate School for Integrative Sciences and Engineering, Singapore 117597.

Abstract

SUMMARY:

Data assimilation (DA) is a computational approach that estimates unknown parameters in a pathway model using time-course information. Particle filtering, the underlying method used, is a well-established statistical method that approximates the joint posterior distributions of parameters by using sequentially generated Monte Carlo samples. In this article, we report the release of Java-based software (DA 1.0) with an intuitive and user-friendly interface to allow users to carry out parameters estimation using DA.

AVAILABILITY AND IMPLEMENTATION:

DA 1.0 was developed using Java and thus would be executable on any platform installed with JDK 6.0 (not JRE 6.0) or later. DA 1.0 is freely available for academic users and can be launched or downloaded from http://da.csml.org.

PMID:
20505000
DOI:
10.1093/bioinformatics/btq276
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Silverchair Information Systems
Loading ...
Support Center