C-Arylation reactions catalyzed by CuO-nanoparticles under ligand free conditions

Beilstein J Org Chem. 2010 Apr 15:6:35. doi: 10.3762/bjoc.6.35.

Abstract

CuO-nanoparticles were found to be an excellent heterogeneous catalyst for C-arylation of active methylene compounds using various aryl halides. The products were obtained in good to excellent yield. The catalyst can be recovered and reused for four cycles with almost no loss in activity.

Keywords: C-arylation; active methylene compounds; heterogeneous catalyst; recyclability.