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Dement Geriatr Cogn Disord. 2010;29(5):413-23. doi: 10.1159/000305099. Epub 2010 May 22.

Vegetables, unsaturated fats, moderate alcohol intake, and mild cognitive impairment.

Author information

1
Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA. roberts.rosebud @ mayo.edu

Abstract

BACKGROUND/AIMS:

To investigate associations of the Mediterranean diet (MeDi) components and the MeDi score with mild cognitive impairment (MCI).

METHODS:

Participants (aged 70-89 years) were clinically evaluated to assess MCI and dementia, and completed a 128-item food frequency questionnaire.

RESULTS:

163 of 1,233 nondemented persons had MCI. The odds ratio of MCI was reduced for high vegetable intake [0.66 (95% CI = 0.44-0.99), p = 0.05] and for high mono- plus polyunsaturated fatty acid to saturated fatty acid ratio [0.52 (95% CI = 0.33-0.81), p = 0.007], adjusted for confounders. The risk of incident MCI or dementia was reduced in subjects with a high MeDi score [hazard ratio = 0.75 (95% CI = 0.46-1.21), p = 0.24].

CONCLUSION:

Vegetables, unsaturated fats, and a high MeDi score may be beneficial to cognitive function.

PMID:
20502015
PMCID:
PMC2889256
DOI:
10.1159/000305099
[Indexed for MEDLINE]
Free PMC Article

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