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Bioinformatics. 2010 Jul 15;26(14):1804-5. doi: 10.1093/bioinformatics/btq264. Epub 2010 May 25.

GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base.

Author information

1
Department of Physiology & Biophysics, Weill Medical College of Cornell University, New York, NY, USA.

Abstract

SUMMARY:

Rapid expansion of available data about G Protein Coupled Receptor (GPCR) dimers/oligomers over the past few years requires an effective system to organize this information electronically. Based on an ontology derived from a community dialog involving colleagues using experimental and computational methodologies, we developed the GPCR-Oligomerization Knowledge Base (GPCR-OKB). GPCR-OKB is a system that supports browsing and searching for GPCR oligomer data. Such data were manually derived from the literature. While focused on GPCR oligomers, GPCR-OKB is seamlessly connected to GPCRDB, facilitating the correlation of information about GPCR protomers and oligomers.

AVAILABILITY AND IMPLEMENTATION:

The GPCR-OKB web application is freely available at http://www.gpcr-okb.org

PMID:
20501551
PMCID:
PMC2894509
DOI:
10.1093/bioinformatics/btq264
[Indexed for MEDLINE]
Free PMC Article
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