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Drug Class Review on Agents for Overactive Bladder: Final Report [Internet].


Portland (OR): Oregon Health & Science University; 2005 Dec.
Drug Class Reviews.

Author information

Oregon Evidence-based Practice Center, Oregon Health & Science University, Mark Helfand, MD, MPH, Director


Overactive bladder syndrome (OAB) is defined by the International Continence Society (ICS) as a medical condition referring to the urinary symptoms of frequency and urgency, with or without urge incontinence, when appearing in the absence of local pathological factors. Nocturia is also commonly present. The purpose of this review is to compare the efficacy, effectiveness, and adverse effects of the pharmacological treatments for OAB. Pharmacological treatment includes darifenacin, flavoxate hydrochloride, hyoscyamine, oxybutynin chloride, tolterodine tartrate, trospium chloride, scopolamine transdermal, and solifenacin succinate.

Copyright & 2005, Oregon Health & Science University, Portland, Oregon.

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