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Nat Med. 2010 Jun;16(6):653-61. doi: 10.1038/nm.2165. Epub 2010 May 23.

Missing pieces in the Parkinson's disease puzzle.

Author information

1
Department of Neurology, ClĂ­nica Universitaria and Medical School of Navarra, Neuroscience Centre, Center for Applied Medical Research, Pamplona, Spain. obeso@unav.es

Abstract

Parkinson's disease is a neurodegenerative process characterized by numerous motor and nonmotor clinical manifestations for which effective, mechanism-based treatments remain elusive. Here we discuss a series of critical issues that we think researchers need to address to stand a better chance of solving the different challenges posed by this pathology.

PMID:
20495568
DOI:
10.1038/nm.2165
[Indexed for MEDLINE]

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