Send to

Choose Destination
Obstet Gynecol Clin North Am. 2010 Mar;37(1):37-46. doi: 10.1016/j.ogc.2010.01.001.

Ashkenazi Jewish screening in the twenty-first century.

Author information

Obstetrics and Gynecology and Women's Health, Albert Einstein, College of Medicine, Bronx, NY, USA.


Ashkenazi Jewish genetic screening has expanded significantly in the past 4 decades. Individuals of Eastern European (Ashkenazi) Jewish (AJ) descent are at increased risk of having offspring with particular genetic diseases that have significant morbidity and mortality. In addition, there are some disorders, such as cystic fibrosis, for which northern European Caucasians are at comparable risk with those of an AJ background. Carrier screening for many of these Jewish genetic disorders has become standard of care. As technology advances, so does the number of disorders for which screening is available. Thus, we need to continue to be cognizant of informed consent, test sensitivity, confidentiality, prenatal diagnosis, preimplantation genetic screening, and public health concerns regarding testing.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center