Format

Send to

Choose Destination
Biochem Biophys Res Commun. 2010 May 21;396(1):135-9. doi: 10.1016/j.bbrc.2010.03.140.

Advances in eicosanoid research, novel therapeutic implications.

Author information

1
Department of Medical Biochemistry and Biophysics, Division of Chemistry 2, Karolinska Institutet, S-17177 Stockholm, Sweden. jesper.haeggstrom@ki.se

Abstract

Eicosanoids are a family of oxygenated metabolites of arachidonic acid, including the prostaglandins, thromboxanes, leukotrienes and lipoxins. These lipid mediators play essential roles in normal cellular homeostasis as well as in a number of disease states. This review will focus on recent advances in the field of eicosanoids and highlight specific discoveries and achievements. Emphasis will be placed on structure and receptor biology, which are of significant pharmacological and clinical relevance.

PMID:
20494126
DOI:
10.1016/j.bbrc.2010.03.140
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center