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Curr Opin Plant Biol. 2010 Aug;13(4):472-7. doi: 10.1016/j.pbi.2010.04.007. Epub 2010 May 17.

NB-LRR proteins: pairs, pieces, perception, partners, and pathways.

Author information

1
Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, NC 27599, USA.

Abstract

In plants, many of the innate immune receptors or disease resistance (R) proteins contain a NB-LRR (Nucleotide-binding site, Leucine-rich repeat) structure. The recent findings regarding NB-LRR signaling are summarized in this article. An emerging theme is that two NB-LRRs can function together to mediate disease resistance against pathogen isolates. Also, recent results delineate the NB-LRR protein fragments that are sufficient to initiate defense signaling. Importantly, distinct fragments of different NB-LRRs are sufficient for function. Finally, we describe the new roles of accessory proteins and downstream host genes in NB-LRR signaling.

PMID:
20483655
PMCID:
PMC2910844
DOI:
10.1016/j.pbi.2010.04.007
[Indexed for MEDLINE]
Free PMC Article

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