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Chem Soc Rev. 2010 Aug;39(8):2835-46. doi: 10.1039/b915574k. Epub 2010 May 17.

Photoactive molecules for applications in molecular imaging and cell biology.

Author information

1
Division of Chemistry & Biological Chemistry, School of Physical & Mathematical Sciences, Nanyang Technological University, Singapore.

Abstract

Photoactive technology has proven successful for non-invasive regulation of biological activities and processes in living cells. With the light-directed generation of biomaterials or signals, mechanisms in cell biology can be investigated at the molecular level with spatial and temporal resolution. In this tutorial review, we aim to introduce the important applications of photoactive molecules for elucidating cell biology on aspects of protein engineering, fluorescence labelling, gene regulation and cell physiological functions.

PMID:
20480074
DOI:
10.1039/b915574k
[Indexed for MEDLINE]

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