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J Cancer Res Ther. 2010 Jan-Mar;6(1):89-91. doi: 10.4103/0973-1482.63562.

Late solitary testicular metastasis from rectal cancer.

Author information

1
Ipswich Hospital NHS, United Kingdom.

Abstract

Isolated testicular metastasis from rectal cancer is rare. We describe the case of a patient who presented with a locally advanced rectal malignancy and underwent multimodality treatment with low anterior resection, postoperative radiotherapy and adjuvant chemotherapy. He developed a painless testicular nodule while on follow-up, five years after the diagnosis of primary rectal cancer. Histopathology and immunohistochemistry of orchidectomy specimen were compatible with a metastatic adenocarcinoma of rectal origin. We hypothesize that this phenomenon of isolated relapse in a sanctuary site could be due to the altered biology and pattern of metastasis as a result of effective adjuvant systemic chemotherapy. Treatment of late isolated relapse in the testis needs to be ascertained.

PMID:
20479555
DOI:
10.4103/0973-1482.63562
[Indexed for MEDLINE]
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