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J Matern Fetal Neonatal Med. 2011 Feb;24(2):280-3. doi: 10.3109/14767058.2010.485233. Epub 2010 May 17.

Seroprevalence of TORCH infections in women of childbearing age in Croatia.

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1
Virology Department, Croatian National Institute of Public Health, Zagreb, Croatia. tatjana.vilibic-cavlek@hzjz.hr

Abstract

During 2005-2009, a seroepidemiological study was carried out in Croatia to define the population susceptible to common TORCH agents among pregnant and non-pregnant women of childbearing age. The IgG seroprevalence was 29.1% forT. gondii, 94.6% for rubella, 75.3% for cytomegalovirus (CMV), 78.7% for herpes simplex virus type 1 (HSV-1), and 6.8% for HSV-2. Acute toxoplasmosis and CMV infection (positive IgM antibodies with low IgG avidity) were documented in 0.25% and 0.09% women, respectively. IgM prevalence was 1.2% for both HSV-1 and HSV-2. None of the participants showed acute rubella infection. Seropositivity to T. gondii and HSV-2 varied significantly between age groups (p = 0.001 and p = 0.036, respectively). Women residing in rural regions showed a significantly higher seroprevalence rate for T. gondii, CMV, and HSV-1 than urban women (T. gondii: 44.0% vs. 25.4%, p < 0.001; CMV: 85.0% vs. 73.1%, p = 0.018; HSV-1: 86.0% vs. 76.4%, p = 0.041).

PMID:
20476874
DOI:
10.3109/14767058.2010.485233
[Indexed for MEDLINE]
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