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Psychiatry Res. 2010 Jun 30;178(1):205-7. doi: 10.1016/j.psychres.2010.04.027. Epub 2010 May 14.

Phase relationships between core body temperature, melatonin, and sleep are associated with depression severity: further evidence for circadian misalignment in non-seasonal depression.

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1
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Abstract

Misalignment between the timing of sleep and the circadian pacemaker has been linked to depression symptoms. This study sought to extend earlier findings by comparing sleep and circadian markers in healthy controls and individuals with major depression. Two markers of circadian misalignment correlated with depression severity in the depressed group.

PMID:
20471106
PMCID:
PMC2914120
DOI:
10.1016/j.psychres.2010.04.027
[Indexed for MEDLINE]
Free PMC Article
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