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Am J Emerg Med. 2010 May;28(4):511-4. doi: 10.1016/j.ajem.2009.04.002. Epub 2010 Mar 25.

Bacterial blood cultures in children with sickle cell disease.

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1
Division of Pediatric Emergency Medicine, BC Children's Hospital, Vancouver, BC, Canada.

Abstract

BACKGROUND:

Children with sickle cell disease (SCD) are considered at risk for bacteremia, especially when they present to the emergency department (ED) with fever.

OBJECTIVE:

We aimed to determine the incidence of bacteremia in children with SCD presenting with or without fever to a pediatric ED.

METHODS:

A retrospective chart review of 692 pediatric ED visits of children with SCD during a 2-year period was conducted.

RESULTS:

Seven blood cultures (6 homozygous and 1 heterozygous) had bacterial growth (1.3%; 95% confidence interval, 0.5-2.1), 3 of which were among febrile children (1.7%; 95% confidence interval, 0-3.6). All identified microorganisms are part of the normal skin or oral flora and could represent contamination. None of the patients had growth of the Streptococcus pneumoniae species.

CONCLUSION:

A very low rate of bacterial growth and no S pneumoniae were found. The absence of S pneumoniae in our cohort can be associated with the addition of the 7-valent pneumococcal conjugate vaccine.

PMID:
20466235
DOI:
10.1016/j.ajem.2009.04.002
[Indexed for MEDLINE]

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