Format

Send to

Choose Destination
Neurol Sci. 2010 Jun;31 Suppl 1:S141-3. doi: 10.1007/s10072-010-0308-3.

Migraine is curable!

Author information

1
Dalhousie University, Halifax, Canada. a.purdy@dal.ca

Abstract

Migraine is a pathophysiologically complex disorder that arises from a neurovascular disturbance in the brain itself, and involves modulatory mechanisms in the brainstem, subcortical and cortical levels to process pain. These processing mechanisms may be abnormal in migraine, which uses otherwise normal neural pathways for pain transmission. Migraine is also an inherited dysfunction that in some individuals becomes chronic, and at various stages has shown functional neuroimaging changes. Based on further analysis of these concepts, it may be that migraine is a potentially curable disorder or disease, or at least one that can be controlled to such an extent as to prevent its acute genesis and chronic progression to the point that it no longer becomes clinically symptomatic. There are many present and potential targets to mitigate the migraine attack(s), and therefore a potential cure might exist in the future, resulting in a reduction of the expression of paroxysmal symptoms and signs, which then will fall within or near the spectrum of normal brain functions. This paper will explore the migraine diatheses to look at ways that migraine could be seen to be curable by either limiting its threshold to clinical expression or stabilizing or even reversing its pathophysiological genesis.

PMID:
20464606
DOI:
10.1007/s10072-010-0308-3
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center