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Nat Prod Rep. 2010 Jul;27(7):996-1047. doi: 10.1039/b816430b. Epub 2010 May 12.

Biosynthesis of polyketides by trans-AT polyketide synthases.

Author information

1
Kekulé Institute of Organic Chemistry and Biochemistry, University of Bonn, Bonn, Germany. joern.piel@uni-bonn.de

Abstract

This review discusses the biosynthesis of natural products that are generated by trans-AT polyketide synthases, a family of catalytically versatile enzymes that have recently been recognized as one of the major group of proteins involved in the production of bioactive polyketides. 436 references are cited.

PMID:
20464003
DOI:
10.1039/b816430b
[Indexed for MEDLINE]

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