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Can Fam Physician. 2010 May;56(5):427-9.

Safety of antihistamines during pregnancy and lactation.

Abstract

QUESTION:

Many of my pregnant and breastfeeding patients suffer from allergies and frequently ask me about the safety of antihistamines during pregnancy and breastfeeding. Should I advise them to use the older sedating medications? I have heard that they might be safer than the newer nonsedating class of drugs. Or have the newer ones been studied as well?

ANSWER:

First-generation antihistamines are considered safe to use during pregnancy. There are relatively fewer data on the nonsedating second-generation antihistamines; however, published studies are reassuring. All antihistamines are considered safe to use during breastfeeding, as minimal amounts are excreted in the breast milk and would not cause any adverse effects on a breastfeeding infant.

PMID:
20463270
PMCID:
PMC2868610
[Indexed for MEDLINE]
Free PMC Article

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