Renal smooth muscle hamartoma

Pathol Res Pract. 2010 Nov 15;206(11):782-4. doi: 10.1016/j.prp.2010.03.009. Epub 2010 May 11.

Abstract

A large (4 cm in diameter) smooth muscle tumor was found in the medial aspect of the right kidney in a 54-year-old Caucasian woman with acute hypertension. Clonality assay (HUMARA) showed no evidence of clonal proliferation, and array comparative genomic hybridization (aCGH) analysis failed to identify any copy number genomic change. These findings are consistent with smooth muscle hamartoma, a rare benign renal tumor-like lesion.

Publication types

  • Case Reports

MeSH terms

  • Clone Cells
  • Comparative Genomic Hybridization
  • DNA / analysis
  • DNA Methylation / genetics
  • Diagnosis, Differential
  • Female
  • Hamartoma / genetics
  • Hamartoma / pathology*
  • Humans
  • Hypertension / diagnosis
  • Hypertension / etiology
  • Kidney Diseases / complications
  • Kidney Diseases / genetics
  • Kidney Diseases / pathology*
  • Leiomyoma / diagnosis
  • Leiomyosarcoma / diagnosis
  • Middle Aged
  • Muscle, Smooth / pathology*
  • Receptors, Androgen / genetics

Substances

  • Receptors, Androgen
  • DNA