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J Am Acad Dermatol. 2010 Jul;63(1):44-51. doi: 10.1016/j.jaad.2009.08.038. Epub 2010 May 11.

Reactive nonsexually related acute genital ulcers: review of cases evaluated at Mayo Clinic.

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1
Division of Clinical Dermatology, Mayo Clinic, Rochester, Minnesota 55905, USA.

Abstract

BACKGROUND:

Reactive nonsexually related acute genital ulcers (RNSRAGU) occur in pubertal girls after an acute systemic infection.

OBJECTIVE:

We sought to characterize RNSRAGU by reviewing the medical records of patients with this disorder.

METHODS:

We searched our medical index database from 1997 to 2007 for RNSRAGU cases. Questionnaires were mailed to identified patients.

RESULTS:

The study included 10 patients; 5 responded to the questionnaire. The mean age at onset was 11.5 years. Vulvar ulcers were preceded by viral gastroenteritis (n = 3), viral upper respiratory tract infection (n = 3), streptococcal pharyngitis (n = 1), influenza (n = 1), and other nonspecific febrile illnesses (n = 2). Seven patients had oral involvement also; 6 had at least one recurrence; and 3 were hospitalized for pain control. Analgesics and topical corticosteroids were the most common treatments. Ulcerations resolved within several weeks in all patients.

LIMITATIONS:

Retrospective study design, small study size, and 50% questionnaire response rate are limitations.

CONCLUSIONS:

Although rare, RNSRAGU should be considered when genital ulceration follows an acute systemic illness.

PMID:
20462661
DOI:
10.1016/j.jaad.2009.08.038
[Indexed for MEDLINE]
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