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Curr Biol. 2010 May 11;20(9):R400-2. doi: 10.1016/j.cub.2010.03.036.

Axon guidance: repulsion and attraction in roundabout ways.

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1
Department of Biological Chemistry, Howard Hughes Medical Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.

Abstract

The secreted signal Slit and its three receptors, Robo1-3, regulate axon guidance in the Drosophila nervous system. Differences in expression and structure of Robo paralogs contribute to diversifying growth cone responses to a common ligand.

PMID:
20462479
DOI:
10.1016/j.cub.2010.03.036
[Indexed for MEDLINE]
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