Format

Send to

Choose Destination
See comment in PubMed Commons below
BMC Microbiol. 2010 May 10;10:137. doi: 10.1186/1471-2180-10-137.

Vibrio chromosomes share common history.

Author information

1
Dept, of Civil and Environmental Engineering, 15 Vassar Street, Cambridge, MA 02139, USA. bckirkup@post.harvard.edu

Abstract

BACKGROUND:

While most gamma proteobacteria have a single circular chromosome, Vibrionales have two circular chromosomes. Horizontal gene transfer is common among Vibrios, and in light of this genetic mobility, it is an open question to what extent the two chromosomes themselves share a common history since their formation.

RESULTS:

Single copy genes from each chromosome (142 genes from chromosome I and 42 genes from chromosome II) were identified from 19 sequenced Vibrionales genomes and their phylogenetic comparison suggests consistent phylogenies for each chromosome. Additionally, study of the gene organization and phylogeny of the respective origins of replication confirmed the shared history.

CONCLUSIONS:

Thus, while elements within the chromosomes may have experienced significant genetic mobility, the backbones share a common history. This allows conclusions based on multilocus sequence analysis (MLSA) for one chromosome to be applied equally to both chromosomes.

PMID:
20459749
PMCID:
PMC2875227
DOI:
10.1186/1471-2180-10-137
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for BioMed Central Icon for PubMed Central
    Loading ...
    Support Center