Format

Send to

Choose Destination
Curr Opin Struct Biol. 2010 Jun;20(3):276-82. doi: 10.1016/j.sbi.2010.03.009. Epub 2010 Apr 22.

Knitting complex weaves with DNA origami.

Author information

1
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA. William_Shih@dfci.harvard.edu

Abstract

The past three decades have witnessed steady growth in our ability to harness DNA branched junctions as building blocks for programmable self-assembly of diverse supramolecular architectures. The DNA-origami method, which exploits the availability of long DNA sequences to template sophisticated nanostructures, has played a major role in extending this trend through the past few years. Today, two-dimensional and three-dimensional custom-shaped nanostructures comparable in mass to a small virus can be designed, assembled, and characterized with a prototyping cycle on the order of a couple of weeks.

PMID:
20456942
PMCID:
PMC2916953
DOI:
10.1016/j.sbi.2010.03.009
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center