Format

Send to

Choose Destination
Nat Methods. 2010 Jun;7(6):447-9. doi: 10.1038/nmeth.1455. Epub 2010 May 9.

Coding of facial expressions of pain in the laboratory mouse.

Author information

1
Department of Psychology and Alan Edwards Centre for Research on Pain, McGill University, Montreal, Quebec, Canada.

Abstract

Facial expression is widely used as a measure of pain in infants; whether nonhuman animals display such pain expressions has never been systematically assessed. We developed the mouse grimace scale (MGS), a standardized behavioral coding system with high accuracy and reliability; assays involving noxious stimuli of moderate duration are accompanied by facial expressions of pain. This measure of spontaneously emitted pain may provide insight into the subjective pain experience of mice.

Comment in

PMID:
20453868
DOI:
10.1038/nmeth.1455
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Nature Publishing Group
Loading ...
Support Center