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Biosci Biotechnol Biochem. 2010;74(4):843-7.

Breeding of a low pyruvate-producing sake yeast by isolation of a mutant resistant to ethyl alpha-transcyanocinnamate, an inhibitor of mitochondrial pyruvate transport.

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1
Faculty of Agriculture, Saga University, Japan.

Abstract

Pyruvate is the key substance controlling the formation of diacetyl, acetaldehyde, and acetate during alcoholic fermentation. Here we report the breeding of a low pyruvate-producing sake yeast by isolation of a mutant resistant to ethyl alpha-transcyanocinnamate, an inhibitor of mitochondrial pyruvate transport. Mitochondrial function was involved in resistance to this substance and in the production of pyruvate by the mutants.

PMID:
20445321
DOI:
10.1271/bbb.90373
[Indexed for MEDLINE]
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