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Arch Dis Child Fetal Neonatal Ed. 2010 May;95(3):F220-4. doi: 10.1136/adc.2008.148205.

Long-term outcome after neonatal hypoxic-ischaemic encephalopathy.

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Department of Neonatology, University Medical Centre Utrecht/Wilhelmina Children's Hospital and Utrecht University, Utrecht, The Netherlands.


Outcome of full-term infants with neonatal encephalopathy of hypoxic-ischemic origin is often assessed in infancy or early childhood and data on outcome in childhood and adolescence is limited. MRI performed in the neonatal period has made a huge contribution to recognition of different patterns of injury. These different patterns of injury are related to the severity of later motor and cognitive disabilities. Long-term follow-up shows that cognitive and memory difficulties may follow even in children without motor deficits. It is therefore recommended to perform follow-up assessment into childhood in children with and without adverse neurological outcome in early infancy.

[Indexed for MEDLINE]

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