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Comput Biol Med. 1991;21(1-2):35-41.

Repeated plasma volume determination with the Evans Blue dye dilution technique: the method and a computer program.

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Danish Aerospace Medical Centre of Research, National Hospital, Copenhagen.

Erratum in

  • Comput Biol Med 1991;21(3):181-91.


This paper describes a reliable multiple sample Evans Blue dye dilution technique and a Pascal program which computes plasma and blood volume on the basis of this technique. The program performs needed corrections and dye disappearance curve fitting. It provides menu-driven facilities for data correction, graphic display of the dye disappearance curve, and print-out of all the involved data. Means +/- S.E.M. for three plasma volume determinations in each of six resting subjects were: 3239 +/- 96 ml, 3189 +/- 81 ml, and 3187 +/- 102 ml. The differences were not statistically significant.

[Indexed for MEDLINE]

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