Format

Send to

Choose Destination
Vaccine. 2010 Jun 11;28(26):4235-48. doi: 10.1016/j.vaccine.2010.04.052. Epub 2010 May 14.

Factors underlying parental decisions about combination childhood vaccinations including MMR: a systematic review.

Author information

1
Centre for Patient Safety and Service Quality, Imperial College London, St. Mary's Hospital Campus, London W2 1NY, United Kingdom. Katrina.Brown@imperial.ac.uk

Abstract

Suboptimal childhood vaccination uptake results in disease outbreaks, and in developed countries is largely attributable to parental choice. To inform evidence-based interventions, we conducted a systematic review of factors underlying parental vaccination decisions. Thirty-one studies were reviewed. Outcomes and methods are disparate, which limits synthesis; however parents are consistently shown to act in line with their attitudes to combination childhood vaccinations. Vaccine-declining parents believe that vaccines are unsafe and ineffective and that the diseases they are given to prevent are mild and uncommon; they mistrust their health professionals, Government and officially-endorsed vaccine research but trust media and non-official information sources and resent perceived pressure to risk their own child's safety for public health benefit. Interventions should focus on detailed decision mechanisms including disease-related anticipated regret and perception of anecdotal information as statistically representative. Self-reported vaccine uptake, retrospective attitude assessment and unrepresentative samples limit the reliability of reviewed data - methodological improvements are required in this area.

PMID:
20438879
DOI:
10.1016/j.vaccine.2010.04.052
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center