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J Dermatolog Treat. 2010 Sep;21(5):301-5. doi: 10.3109/09546630903277628.

Ex vivo study of the home-use TriPollar RF device using an experimental human skin model.

Author information

1
Pitié Salpétrière Hospital, Paris, France. gredeco@orange.fr

Abstract

BACKGROUND:

A wide variety of professional radio frequency (RF) aesthetic treatments for anti-aging are available aiming at skin tightening. A new home-use RF device for facial treatments has recently been developed based on TriPollar technology.

OBJECTIVE:

To evaluate the mechanism of the new home-use device, in the process of collagen remodeling, using an ex vivo skin model.

METHODS:

Human skin samples were collected in order to evaluate the anti-aging effect of a home-use device for facial treatments on an ex vivo human skin model. Skin tightening was evaluated by dermal histology, quantitative analysis of collagen fibers and dosage of collagen synthesis.

RESULTS:

Significant collagen remodeling following RF treatment with the device was found in the superficial and mid-deep dermis. Biochemical measurement of newly synthesized collagen showed an increase of 41% in the treated samples as compared to UV-aged control samples.

CONCLUSIONS:

The new home-use device has been demonstrated to affect significant collagen remodeling, in terms of the structural and biochemical improvement of dermal collagen on treated skin samples.

PMID:
20438388
DOI:
10.3109/09546630903277628
[Indexed for MEDLINE]

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