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Physiology (Bethesda). 2010 Apr;25(2):72-84. doi: 10.1152/physiol.00001.2010.

Lessons from photoreceptors: turning off g-protein signaling in living cells.

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1
Departments of Ophthalmology and Vision Science, University of California, Davis, California, USA. meburns@ucdavis.edu

Abstract

Phototransduction in retinal rods is one of the most extensively studied G-protein signaling systems. In recent years, our understanding of the biochemical steps that regulate the deactivation of the rod's response to light has greatly improved. Here, we summarize recent advances and highlight some of the remaining puzzles in this model signaling system.

PMID:
20430952
PMCID:
PMC2880230
DOI:
10.1152/physiol.00001.2010
[Indexed for MEDLINE]
Free PMC Article
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