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Clin Biochem. 2010 Jul;43(10-11):887-90. doi: 10.1016/j.clinbiochem.2010.04.061. Epub 2010 Apr 27.

Natural anti-inflammatory products and leukotriene inhibitors as complementary therapy for bronchial asthma.

Author information

1
Department of Biochemistry, Faculty of Pharmacy, University of Beni Sueif, Beni Sueif 62514, Egypt. mahahoussen@yahoo.com

Abstract

OBJECTIVE:

To assess the efficacy of a combination of Boswellia serrata, licorice root (Glycyrrhiza glabra) and Tumeric root (Curcuma longa) as natural leukotriene inhibitor, antiinflammatory and antioxidant products respectively in controlling bronchial asthma.

SUBJECTS AND METHODS:

The study comprised 63 patients with bronchial asthma that are further subdivided into two groups .Group 1 receiving oral capsule (combined herb) in a soft-gelatin capsule 3 times daily for 4weeks and group 2 receiving placebo. Plasma leukotriene C(4) (LTC(4))(,) nitric oxide (NO) and malondialdehyde (MDA) levels were measured and pulmonary function was also assessed in all patients enrolled in the study.

RESULTS:

There was a statistically significant decrease in the plasma levels of LTC(4), (MDA), and NO in target therapy group when compared with placebo group.

CONCLUSION:

The used extract contained Boswellia serrata, Curcuma longa and Glycyrrhiza has a pronounced effect in the management of bronchial asthma.

[Indexed for MEDLINE]

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