Abstract
The most common Helicobacter pylori genotype among 37 U.S. children was cagA positive, vacA s1m1, and oipA "on" (n = 17, 45.9%), followed by cagA negative, vacA s2m2, and oipA "off" (n = 8, 21.6%), similar to the pattern in adults. cagA positivity was more common in blacks than in whites (i.e., 100% versus 56.5%, P = 0.032).
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Adolescent
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Antigens, Bacterial / genetics
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Bacterial Proteins / genetics
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Child
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Child, Preschool
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Disease Susceptibility
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Genotype
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Helicobacter Infections* / ethnology
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Helicobacter Infections* / microbiology
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Helicobacter pylori* / genetics
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Helicobacter pylori* / pathogenicity
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Humans
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Racial Groups / ethnology*
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United States
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Virulence Factors / genetics*
Substances
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Antigens, Bacterial
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Bacterial Proteins
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Virulence Factors
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cagA protein, Helicobacter pylori