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Chem Soc Rev. 2010 May;39(5):1747-63. doi: 10.1039/b714449k. Epub 2010 Feb 1.

Electrochemical biosensors.

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Department of Chemistry, Benedictine University, 5700 College Road, Lisle, IL 60532-0900, USA.


Electrochemical biosensors combine the sensitivity of electroanalytical methods with the inherent bioselectivity of the biological component. The biological component in the sensor recognizes its analyte resulting in a catalytic or binding event that ultimately produces an electrical signal monitored by a transducer that is proportional to analyte concentration. Some of these sensor devices have reached the commercial stage and are routinely used in clinical, environmental, industrial, and agricultural applications. The two classes of electrochemical biosensors, biocatalytic devices and affinity sensors, will be discussed in this critical review to provide an accessible introduction to electrochemical biosensors for any scientist (110 references).

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