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Clin Exp Immunol. 2010 Apr;160(1):85-91. doi: 10.1111/j.1365-2249.2010.04124.x.

99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: psycho-neuroimmunology and the intestinal microbiota: clinical observations and basic mechanisms.

Author information

1
Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.

Abstract

This is a rapidly emerging field. The application of knowledge regarding the relationship between neural and immune systems in order to gain a better understanding of human conditions has been slow. In this discussion we describe how the brain and microbiota interact, and try to bring this into a context that is clinically relevant. We begin by describing established facts pertaining to the gut-brain axis and the role of gut bacteria. We then focus upon emerging data that will contribute to the generation of a new conceptual framework about the microbiota-gut-brain axis. In the final section we anticipate future directions of this field.

PMID:
20415856
PMCID:
PMC2841840
DOI:
10.1111/j.1365-2249.2010.04124.x
[Indexed for MEDLINE]
Free PMC Article

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