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Diabetes Care. 2010 Jul;33(7):1497-9. doi: 10.2337/dc09-2310. Epub 2010 Apr 22.

Prevalence and determinant factors of sarcopenia in patients with type 2 diabetes: the Korean Sarcopenic Obesity Study (KSOS).

Author information

1
Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, Korea University, Seoul, Korea.

Erratum in

  • Diabetes Care. 2010 Oct;33(10):2294.

Abstract

OBJECTIVE:

We examined prevalence of sarcopenia in Korean patients with type 2 diabetes and compared body compositional parameters between subjects with and without type 2 diabetes.

RESEARCH DESIGN AND METHODS:

The Korean Sarcopenic Obesity Study (KSOS) included 810 subjects (414 patients with diabetes and 396 control subjects) who were examined using dual-energy X-ray absorptiometry. Prevalence of sarcopenia was defined using the skeletal muscle index (SMI).

RESULTS:

Prevalence in patients with diabetes and in the control group was 15.7 and 6.9%, respectively. In both men and women, SMI values were significantly decreased in patients with diabetes compared with subjects without diabetes. Furthermore, multiple logistic regression analysis showed that type 2 diabetes was independently associated with sarcopenia.

CONCLUSIONS:

Type 2 diabetes was associated with increased risk of sarcopenia. These characteristics may contribute to physical disability and metabolic disorders in older adults with diabetes.

PMID:
20413515
PMCID:
PMC2890348
DOI:
10.2337/dc09-2310
[Indexed for MEDLINE]
Free PMC Article

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