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Anaerobe. 2010 Aug;16(4):393-5. doi: 10.1016/j.anaerobe.2010.04.001. Epub 2010 Apr 20.

Clostridium difficile toxinotype XI (A-B-) exhibits unique arrangement of PaLoc and its upstream region.

Author information

1
Department of Biology, Biotechnical Faculty, University of Ljubljana, Vecna pot 111, Ljubljana, Slovenia. barbara.geric@guest.arnes.si

Abstract

Clostridium difficile toxinotype XI strains do not produce toxins A (TcdA) or B (TcdB) but do possess a nonfunctional remnant of the pathogenicity locus (PaLoc), bearing part of the sequence for tcdA. This is the first report of a type with absent upstream terminal PaLoc sequences and major genetic rearrangements of the PaLoc region.

PMID:
20412866
DOI:
10.1016/j.anaerobe.2010.04.001
[Indexed for MEDLINE]

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