First description of an extended-spectrum-beta-lactamase-producing multidrug-resistant Escherichia fergusonii strain in a patient with cystitis

Philippe R S Lagacé-Wiens; Patricia J Baudry; Paulette Pang; Gregory Hammond

doi:10.1128/JCM.00364-10

First description of an extended-spectrum-beta-lactamase-producing multidrug-resistant Escherichia fergusonii strain in a patient with cystitis

J Clin Microbiol. 2010 Jun;48(6):2301-2. doi: 10.1128/JCM.00364-10. Epub 2010 Apr 21.

Authors

Philippe R S Lagacé-Wiens¹, Patricia J Baudry, Paulette Pang, Gregory Hammond

Affiliation

¹ Department of Medical Microbiology and Infectious Diseases, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada. plagacewiens@sbgh.mb.ca

Abstract

Extended-spectrum-beta-lactamase (ESBL)-producing organisms have captured the attention of clinicians and laboratorians and are agents of nosocomial and community onset infections (J. D. Pitout and K. B. Laupland, Lancet Infect. Dis. 8:159-166, 2008). ESBLs in many enterobacteriaceae and in nonfermenting Gram-negative organisms have been described (K. Bush and G. A. Jacoby, Antimicrob. Agents Chemother. 54:969-976, 2010). We present the first case of a clinical isolate of multidrug-resistant Escherichia fergusonii expressing an extended-spectrum-beta-lactamase (ESBL).

Publication types

Case Reports

MeSH terms

Aged
Anti-Bacterial Agents / pharmacology
Cystitis / microbiology*
Drug Resistance, Multiple, Bacterial*
Enterobacteriaceae Infections / diagnosis*
Enterobacteriaceae Infections / microbiology
Escherichia / classification*
Escherichia / drug effects
Escherichia / enzymology*
Escherichia / isolation & purification
Female
Humans
Microbial Sensitivity Tests
beta-Lactamases / biosynthesis*

Substances

Anti-Bacterial Agents
beta-Lactamases