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Clin Cancer Res. 2010 May 1;16(9):2486-8. doi: 10.1158/1078-0432.CCR-10-0397. Epub 2010 Apr 20.

Imaging breast cancer chemotherapy response with light. Commentary on Soliman et al., p. 2605.

Author information

  • 1Laser Microbeam and Medical Program, Beckman Laser Institute and Medical Clinic, University of California, Irvine, CA 92715, USA. bjtrombe@uci.edu

Abstract

Diffuse optical spectroscopy (DOS), which is used to image tumor metabolic response to neoadjuvant chemotherapy (NAC), shows large changes in tumor functional parameters with significant reductions in oxy- and deoxyhemoglobin for responders versus nonresponders. Although investigational, DOS may provide a cost-effective, risk-free method for optimizing NAC drug and dosing strategies for individual patients.

PMID:
20406838
PMCID:
PMC3204881
DOI:
10.1158/1078-0432.CCR-10-0397
[PubMed - indexed for MEDLINE]
Free PMC Article
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