Format

Send to

Choose Destination
See comment in PubMed Commons below
Br J Clin Pharmacol. 2010 Apr;69(4):367-78. doi: 10.1111/j.1365-2125.2009.03610.x.

The application of mass-spectrometry-based protein biomarker discovery to theragnostics.

Author information

1
Centre for Cardiovascular Science, Edinburgh University, Queen's Medical Research Institute, UK.

Abstract

Over the last decade rapid developments in mass spectrometry have allowed the identification of multiple proteins in complex biological samples. This proteomic approach has been applied to biomarker discovery in the context of clinical pharmacology (the combination of biomarker and drug now being termed 'theragnostics'). In this review we provide a roadmap for early protein biomarker discovery studies, focusing on some key questions that regularly confront researchers.

PMID:
20406221
PMCID:
PMC2848410
DOI:
10.1111/j.1365-2125.2009.03610.x
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Wiley Icon for PubMed Central
    Loading ...
    Support Center