Format

Send to

Choose Destination
Ann Biomed Eng. 2010 Aug;38(8):2542-52. doi: 10.1007/s10439-010-0027-1. Epub 2010 Apr 20.

Symbolic dynamic analysis of relations between cardiac and breathing cycles in patients on weaning trials.

Author information

1
Departament ESAII, Universitat Politècnica de Catalunya (UPC), Pau Gargallo, 5, 08028 Barcelona, Spain.

Abstract

Traditional time-domain techniques of data analysis are often not sufficient to characterize the complex dynamics of the cardiorespiratory interdependencies during the weaning trials. In this paper, the interactions between the heart rate (HR) and the breathing rate (BR) were studied using joint symbolic dynamic analysis. A total of 133 patients on weaning trials from mechanical ventilation were analyzed: 94 patients with successful weaning (group S) and 39 patients that failed to maintain spontaneous breathing (group F). The word distribution matrix enabled a coarse-grained quantitative assessment of short-term nonlinear analysis of the cardiorespiratory interactions. The histogram of the occurrence probability of the cardiorespiratory words presented a higher homogeneity in group F than in group S, measured with a higher number of forbidden words in group S as well as a higher number of words whose probability of occurrence is higher than a probability threshold in group S. The discriminant analysis revealed the best results when applying symbolic dynamic variables. Therefore, we hypothesize that joint symbolic dynamic analysis provides enhanced information about different interactions between HR and BR, when comparing patients with successful weaning and patients that failed to maintain spontaneous breathing in the weaning procedure.

PMID:
20405218
PMCID:
PMC2900596
DOI:
10.1007/s10439-010-0027-1
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Springer Icon for PubMed Central
Loading ...
Support Center