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Cell. 2010 Apr 16;141(2):220-2. doi: 10.1016/j.cell.2010.03.047.

Ubiquitin gets CARDed.

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1
Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.

Abstract

Ubiquitin-dependent processes are critical for propagating antiviral defense signals during viral infection. In this issue, Zeng et al. (2010) describe how viral RNA and unanchored ubiquitin chains conspire to promote activation of RIG-I and the host cell's antiviral transcriptional program.

PMID:
20403317
DOI:
10.1016/j.cell.2010.03.047
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