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CNS Spectr. 2010 Jan;15(1 Suppl 1):2-5; discussion 6.

L-methylfolate, methylcobalamin, and N-acetylcysteine in the treatment of Alzheimer's disease-related cognitive decline.

Author information

1
Cardiff University, Cardiff School of Medicine, North Wales, United Kingdom.

Abstract

Neuroinflammatory oxidative stress occurs early in AD pathology. Elevated blood Hcy is a useful marker for such neuroinflammation. Hcy contributes to pathological cascades involving AP and NFTs. In AD, Hcy should be lowered by B-vitamin supplements and NAC.

PMID:
20397369
DOI:
10.1017/s1092852900027589
[Indexed for MEDLINE]

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