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Case Rep Med. 2010;2010:708348. doi: 10.1155/2010/708348. Epub 2010 Apr 8.

Relapsed mantle cell lymphoma presenting as "sister Mary joseph nodule".

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  • 1Department of Internal Medicine, University of Washington, Box 39892. 325 Ninth Ave., Seattle, WA 98104, USA.

Abstract

The finding of umbilical metastasis has historically been called a "Sister Mary Joseph Nodule". A few case reports of lymphoma presenting in this manner have been documented. We report a case of relapsed mantle cell lymphoma (MCL) presenting as a Sister Mary Joseph's nodule. Although the few reports of lymphoma exhibiting umbilical metastasis suggest that patients may still expect a reasonable response to chemotherapy, this patient experienced multiple relapses, despite aggressive chemotherapy regimens. This clinical course is characteristic of the mantle cell form of non-hodgkin's lymphoma and illustrates a need to seek out more effective therapies.

PMID:
20396390
PMCID:
PMC2852603
DOI:
10.1155/2010/708348
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