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Curr Biol. 2010 Apr 13;20(7):R324-7. doi: 10.1016/j.cub.2010.02.043.

Apoptosis: conserved roles for integrins in clearance.

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1
UMDNJ-New Jersey Medical School, Newark, NJ 07103, USA.

Abstract

A recent study shows that one of the two known Caenorhabditis elegans homologs of the mammalian integrin alpha subunit plays an essential role in the clearance of apoptotic cells - efferocytosis - during nematode development. These new findings reveal that integrins have evolutionarily conserved functions in efferocytosis in metazoans.

PMID:
20392425
DOI:
10.1016/j.cub.2010.02.043
[Indexed for MEDLINE]
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