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Pak J Biol Sci. 2009 Oct 1;12(19):1299-306.

A diet rich in leafy vegetable fiber improves cholesterol metabolism in high-cholesterol fed rats.

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1
Department of Food Science and Nutrition, National Research Center, P.O. Box 12311, Giza, Egypt.

Abstract

In the present study, the hypocholesterolemic effect of leaf vegetable (Jew's mallow) was studied in high-cholesterol fed rats. The animals were fed diets supplemented with cholesterol (0.25%) for 4 weeks. Leaf vegetable diet produced an important hypocholesterolemic action: it led to a significant lowering (p<0.05) of cholesterol in the plasma and liver, as well as of the atherogenic index and a significant increase (p<0.05) in cecal short chain fatty acids, with respect to the control group. Concurrently, total fecal neutral sterols in the excretion increased (p<0.05) and apparent absorption of dietary cholesterol was significantly depressed (-58%). The consumption of leaf vegetable (Jew's mallow) with a hypercholesterolemic diet improved the lipidemic profile and increased excretion of the total cholesterol end-products.

PMID:
20387744
[Indexed for MEDLINE]
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