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Ukr Biokhim Zh (1999). 2009 Sep-Oct;81(5):58-65.

[Influence of prothrombin cleavage products on platelet activation and aggregation].

[Article in Ukrainian]

Abstract

Meizothrombin efficiently activates mechanically triggered platelets and enhance collagen-, ADP- and adrenalin-induced aggregation of platelet-rich blood plasma. Thus, in clotting system activation zone meizothrombin is able to enhance process of involving platelets in clotformation. Pre-thrombin 1 inhibits collagen-, ADP- and adrenalin-induced aggregation of platelet-rich blood plasma and so regulates not only plasm but platelet hemostasis by reverse negative relation.

PMID:
20387648
[Indexed for MEDLINE]

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