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Int J Mol Sci. 2010 Feb 4;11(2):622-46. doi: 10.3390/ijms11020622.

Biological activities of polyphenols from grapes.

Author information

1
Department of Nutrition, Sun Yat-Sen University, Guangzhou, China. enqinxia@163.com

Abstract

The dietary consumption of grape and its products is associated with a lower incidence of degenerative diseases such as cardiovascular disease and certain types of cancers. Most recent interest has focused on the bioactive phenolic compounds in grape. Anthocyanins, flavanols, flavonols and resveratrol are the most important grape polyphenols because they possess many biological activities, such as antioxidant, cardioprotective, anticancer, anti-inflammation, antiaging and antimicrobial properties. This review summarizes current knowledge on the bioactivities of grape phenolics. The extraction, isolation and identification methods of polyphenols from grape as well as their bioavailability and potential toxicity also are included.

KEYWORDS:

anti-inflammation activity; anticancer activity; antimicrobial effect; antioxidant activity; bioactivity; cardioprotective action; grape; polyphenol

PMID:
20386657
PMCID:
PMC2852857
DOI:
10.3390/ijms11020622
[Indexed for MEDLINE]
Free PMC Article
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